Age Management Medicine
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PREGNENOLONE

Pregnenolone is a steroid hormone synthesized from cholesterol mainly by the adrenal glands and in small part by our nervous system.

What does it do?
There is speculation as to the main role of pregnenolone in the body. Most researchers are now in agreement that the primary role of pregnenolone is as the precursor (the building block) of our other hormones including the estrogens, progesterone, testosterone and DHEA.

DHEA is considered the "daughter" hormone of pregnenolone. Indeed pregneolone is considered by some to be the “mother of all steroid hormones.”

It has been suggested by human and animal studies that pregnenolone may assist:
-Memory enhancement
-Feelings of well being
-Intelligence by increasing ability to acquire knowledge
-Reduction of physical and mental effects of stress
-Mood improvement
-Energy improvement
-Reduction of PMS and menopausal symptoms
-Better sleep and deeper sleep
-Reduction of wrinkles through skin hydration
-As an anti-inflammatory, and with benefits for rheumatoid arthritis

Pregnenolone supplementation
As do our other hormones, pregnenolone levels decline with age. In our seventies, many produce up to 60% less pregnenolone than we did in our thirties. Many physicians and scientists believe that replacement of pregnenolone to those levels of our thirties can help with the symptoms regularly attributed to aging.

Another aspect of pregnenolone that researchers find intriguing is that pregnenolone levels may regulate the levels of our other hormones. In other words, supplementation of pregnenolone may positively impact decreased levels of our other hormones and restore them to more optimal levels.

There is a negative. If increasing pregnenolone levels increases the body's own ability to make hormones, such as DHEA, then concurrent supplementation can theoretically raise other hormone levels too high. This is yet another reason why self-administering any hormone is not advisable and should be done only after levels are drawn and analyzed by an age management specialist.

Pregnenolone Research


Ageless - Suzanne Somers
"As my personal sports doctor, (Dr. Darrow) has never given me a drug for any of my injuries. He is of the thinking that unless a drug is necessary, it is better to allow inflammation to do nature's work." (page 130).


Marc Darrow, M.D.,J.D.,Q.M.E.

Marc Darrow, M.D., J.D.,
is an Assistant Clinical Professor at UCLA School of Medicine. He is a world recognized specialist in many chronic disorders. He has been featured in national publications, and television and radio shows, for his innovative approach to medicine. Dr. Darrow has helped create an age management program for those individuals interested in maintaining a youthful, healthy vigor for adults through “middle age” and well into the senior years.

Patient Information

Joint Rehabilitation and Prolotherapy Information

Marc Darrow, M.D.,J.D.,Q.M.E.
Marc Darrow, M.D., J.D.,
is an Assistant Clinical Professor at UCLA School of Medicine. He is a world recognized specialist in many chronic disorders. He has been featured in national publications, and television and radio shows, for his innovative approach to medicine. As the medical director of Joint Rehab Center, Inc. in West Los Angeles, Dr. Darrow has helped create an age management program for those individuals interested in maintaining a youthful, healthy vigor for adults through “middle age” and well into the senior years.

Why am I so driven to work in the age management field?
Basically it was for my own personal, mental, and spiritual well being. Read what Dr. Darrow has to say about how he got interested in age management!

DISCLAIMER:
Neither Dr. Darrow, nor any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC offer medical advice from this website. This information is offered for educational purposes only. Do not act or rely upon our information without seeking independent professional medical advice. The information on this website does not create a physician-patient relationship between you and Dr. Darrow or any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC. Neither Dr. Darrow, nor any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC guarantees the accuracy, completeness, usefulness, or adequacy of any resources, information, apparatus, product, or process available at or from this website. MEDICAL MODALITIES MENTIONED ARE MEDICAL TECHNIQUES THAT MAY NOT BE CONSIDERED MAINSTREAM. AS WITH ANY MEDICAL PROCEDURE, RESULTS WILL VARY AMONG INDIVIDUALS, AND THERE COULD BE SUBSTANTIAL RISKS INVOLVED. THESE CONCERNS SHOULD BE DISCUSSED WITH YOUR HEALTH CARE PROVIDER PRIOR TO ANY TREATMENT SO THAT YOU HAVE PROPER INFORMED CONSENT AND UNDERSTAND THAT THERE ARE NO GUARANTEES TO HEALING.

Certain studies including the Woman's Health Initiative suggest that hormone supplementation may increase the risk of certain cancers, heart disease, stroke and other ailments. These risks should be discussed with your health care professional while deciding on, implementing, or continuing Hormone Replacement Therapy (HRT)

The option to use Human Identical Hormones or Bio-identical hormones should also be discussed with your medical care provider as there is not sufficient medical evidence at this time to suggest that they are safer than synthetic hormones and may pose equal risk.

If you have or suspect that you have a medical problem, condition or issue, promptly contact your health care provider. The statements on this website have not been evaluated by the Food and Drug Administration. The photos in this Web site feature models for illustrative purposes.