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Selected
research:
Hypothyroidim, quality
of life and mental health
Larisch R, Kley K, Nikolaus S, et
al. Depression and anxiety in different thyroid function states.
Horm Metab Res. 2004 Sep;36(9):650-3
Study
purpose: The researchers stated: "Previous studies on
hypothyroid subjects have indicated serious psychiatric symptoms
affecting the patients' quality of life. The present prospective
cross-sectional study's aim was to examine these symptoms in
thyroid patients with different functional states."
They noted:
"Hypothyroidism represents a widely underestimated
functional condition that may severely affect mental health."
Cognitive function
Prinz PN, Scanlan JM, Vitaliano
PP, et al. Thyroid hormones: positive relationships with
cognition in healthy, euthyroid older men. J Gerontol A Biol Sci
Med Sci. 1999 Mar;54(3):M111-6.
Study:
The researchers acknowledged the well know link between
hypothyroidism and cognitive function. What they sought to
uncover was thyroid levels and cognitive function in elderly men
with "normal" thyroid function.
The
Researchers stated: "Our data suggest that older subjects
may require circulating thyroid hormones in middle to high
levels in order to maintain optimal brain function."
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Heart Disease
Klein I, Ojamaa K. Thyroid hormone
treatment of congestive heart failure. Am J Cardiol.
1998;81:443-7.
Study:
An editorial discussing the effects of hypothyroidism on
heart disease with special emphasis on T3.
T3 and T4
Supplementation
Hennemann G, Docter R, Visser TJ,
et al. Thyroxine plus low-dose, slow-release triiodothyronine
replacement in hypothyroidism: proof of principle. Thyroid
2004;14:271-275
Study:
Examination of the effects of T4 and T3 supplementation
in hypothyroid patients.
The
researchers noted: “In the study reported here we show
that treatment of hypothyroid subjects with a combination of
T(4) plus slow-release T(3) leads to a considerable improvement
of serum T(4) and T(3) values, the T(4)/T(3) ratio and serum TSH
as compared to treatment with T(4)- only. Serum T(3)
administration with slow-release T(3) did not show serum peaks,
in contrast to plain T(3).”
Subclinical thyroid
disease
Elte JW, Mudde AH, Nieuwenhuijzen
Kruseman AC. Subclinical thyroid disease. Postgrad Med J.
1996;72:141-6
Study:
A review article on the "clinical effects, prognostic
significance and the need for and response to therapy," of
subclinical thyroid disease.
Thyroid Main Page
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