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Hormones, Oxidative Stress, Menopause

April 12, 2011 by  
Filed under Menopause

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In the News…
Researchers writing in Clinica Chimica Acta, the International Journal of Clinical Chemistry and Applied Molecular Biology suggest that Hormone Replacement therapy may play a beneficial role in the protection against oxidative stress.

Clin Chim Acta. 2006 Jul;369(1):73-7. Epub 2006 Feb 10.
Unfer TC, Conterato GM, da Silva JC, Duarte MM, Emanuelli T. Influence of hormone replacement therapy on blood antioxidant enzymes in menopausal women. Clin Chim Acta. 2006 Jul;369(1):73-7. Epub 2006 Feb 10.

From the abstract:
BACKGROUND: Natural loss of estrogen occurring in menopausal process may contribute to various health problems many of them possibly related to oxidative stress. Hormone replacement therapy (HRT) is the most common treatment to attenuate menopausal disturbances. This study was aimed at evaluating the influence of HRT on the activity of antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT; and glutathione peroxidase, GPx) and lipid peroxidation (thiobarbituric acid reactive substances, TBARS) in menopausal women.

CONCLUSIONS: HRT antagonizes the decrease of SOD activity that occurs after menopause, suggesting that HRT may play a beneficial role in the protection against oxidative stress.

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Written by Dr. Marc Darrow, M.D.

Dr. Darrow is a world recognized specialist in many chronic disorders. He has been featured in national publications, and television and radio shows, for his innovative approach to medicine. As the medical director of the Darrow Wellness Institute in West Los Angeles, Dr. Darrow has helped create an age management program for those individuals interested in maintaining a youthful, healthy vigor for adults through “middle age” and well into the senior years.

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