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More Body Mass…Diminished Testosterone

April 12, 2011 by  
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Osuna C JA, Gomez-Perez R, Arata-Bellabarba G, Villaroel V. Relationship between bmi, total testosterone, sex hormone-binding-globulin, leptin, insulin and insulin resistance in obese men. Arch Androl. 2006 Sep-Oct;52(5):355-61

From the study abstract: The objective of this work was to evaluate the relationship between sex steroid hormones, sex hormone-binding-globulin, leptin, insulin and insulin resistance in obese men. Anthropometrical indexes, total testosterone, free testosterone, estradiol, sex hormone-binding-globulin (SHBG), glucemia, insulin and leptin were measured in 77 men, with ages between 20 and 60 years.

According to their body mass index (BMI), subjects were grouped into three categories: normal body weight, overweight and obese group.

Total testosterone and SHBG concentrations were lower in the obese group compared with normal and overweight subjects.

The mean insulin concentration was significantly higher in the obese group compared with the other groups.

Our results shows that in a sample of men, total testosterone and SHBG concentrations proportionally diminished with both the increase of BMI and insulin resistance index.

Written by Dr. Marc Darrow, M.D.

Dr. Darrow is a world recognized specialist in many chronic disorders. He has been featured in national publications, and television and radio shows, for his innovative approach to medicine. As the medical director of the Darrow Wellness Institute in West Los Angeles, Dr. Darrow has helped create an age management program for those individuals interested in maintaining a youthful, healthy vigor for adults through “middle age” and well into the senior years.

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