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Hormones, Oxidative Stress, Menopause

Researchers writing in Clinica Chimica Acta, the International Journal of Clinical Chemistry and Applied Molecular Biology suggest that Hormone Replacement therapy may play a beneficial role in the protection against oxidative stress.

Clin Chim Acta. 2006 Jul;369(1):73-7. Epub 2006 Feb 10.
Unfer TC, Conterato GM, da Silva JC, Duarte MM, Emanuelli T. Influence of hormone replacement therapy on blood antioxidant enzymes in menopausal women. Clin Chim Acta. 2006 Jul;369(1):73-7. Epub 2006 Feb 10.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=16472795

From the abstract:
BACKGROUND: Natural loss of estrogen occurring in menopausal process may contribute to various health problems many of them possibly related to oxidative stress. Hormone replacement therapy (HRT) is the most common treatment to attenuate menopausal disturbances. This study was aimed at evaluating the influence of HRT on the activity of antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT; and glutathione peroxidase, GPx) and lipid peroxidation (thiobarbituric acid reactive substances, TBARS) in menopausal women.

CONCLUSIONS: HRT antagonizes the decrease of SOD activity that occurs after menopause, suggesting that HRT may play a beneficial role in the protection against oxidative stress.

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Marc Darrow, M.D.,J.D.,Q.M.E.

Marc Darrow, M.D., J.D.,
is an Assistant Clinical Professor at UCLA School of Medicine. He is a world recognized specialist in many chronic disorders. He has been featured in national publications, and television and radio shows, for his innovative approach to medicine. As the medical director of Joint Rehab Center, Inc. in West Los Angeles, Dr. Darrow has helped create an age management program for those individuals interested in maintaining a youthful, healthy vigor for adults through “middle age” and well into the senior years.


Why am I so driven to work in the age management field? Basically it was for my own personal, mental, and spiritual well being.
Read what Dr. Darrow has to say about how he got interested in age management!

DISCLAIMER:
Neither Dr. Darrow, nor any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC offer medical advice from this website. This information is offered for educational purposes only. Do not act or rely upon our information without seeking independent professional medical advice. The information on this website does not create a physician-patient relationship between you and Dr. Darrow or any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC. Neither Dr. Darrow, nor any associate of JOINT REHAB AND SPORTS MEDICAL CENTER, INC guarantees the accuracy, completeness, usefulness, or adequacy of any resources, information, apparatus, product, or process available at or from this website. MEDICAL MODALITIES MENTIONED ARE MEDICAL TECHNIQUES THAT MAY NOT BE CONSIDERED MAINSTREAM. AS WITH ANY MEDICAL PROCEDURE, RESULTS WILL VARY AMONG INDIVIDUALS, AND THERE COULD BE SUBSTANTIAL RISKS INVOLVED. THESE CONCERNS SHOULD BE DISCUSSED WITH YOUR HEALTH CARE PROVIDER PRIOR TO ANY TREATMENT SO THAT YOU HAVE PROPER INFORMED CONSENT AND UNDERSTAND THAT THERE ARE NO GUARANTEES TO HEALING.

Certain studies including the Woman's Health Initiative suggest that hormone supplementation may increase the risk of certain cancers, heart disease, stroke and other ailments. These risks should be discussed with your health care professional while deciding on, implementing, or continuing Hormone Replacement Therapy (HRT)

The option to use Human Identical Hormones or Bio-identical hormones should also be discussed with your medical care provider as there is not sufficient medical evidence at this time to suggest that they are safer than synthetic hormones and may pose equal risk.

If you have or suspect that you have a medical problem, condition or issue, promptly contact your health care provider. The statements on this website have not been evaluated by the Food and Drug Administration. The photos in this Web site feature models for illustrative purposes.